Fluoride at very low levels destroys at least 66 out of 83 enzymes (p. 53, GTBD) by uncoupling the hydrogen bond linkage between the enzyme coils.  Fluoride causes 113 known ailments (p. 54, GTBD).  Ten of these were established through double blind studies, which although noteworthy, may be of no more significance than the individual diagnoses.

Fluoride in the gels used (inappropriately) to harden the enamel is extremely toxic at a concentration of 13,000 ppm (1.3%).  Keith Kantor of McMinneville Oregon was killed in the dentist's chair 3 years ago by swallowing half a teaspoon of the gel.  His brother nearly died from the same treatment, but was saved by having calcium gluconate administered to him.

Three kidney dialysis patients at the University of Chicago Medical School were killed 3 years ago when nurses used unpurified Chicago tap water for dialysis. Chicago water has 2 ppm fluoride in it during the winter.  Fluoridated water is lethal to dialysis patients.    Fluoride is also very harmful to the kidneys of ordinary people.

One can look up the lethal dose of a large number of chemicals all the way from botulinum and snake poison toxins to sugar, a non-toxin, on pages 57and 58 of my book GTBD.  It is interesting that the lethal dosage of fluoride compound for a 50 kg man is 2.5 mg (fluoroacetic acid), and 400 mg for arsenic oxide.  Numerous people, animals and fish on earth, especially in the U.S., have been killed by fluoride, but very few, if any, by arsenic.

Toothpaste companies now are required to put warning signs on tubes so children will not consume enough of the 1000 ppm (.1%) material to make them sick or cause death.  This requirement arises out of lawsuits in which children were poisoned by fluoride-containing toothpaste.

The best available data indicates about 120,000 cancer patients are killed annually because of fluoride in their drinking water. Flouride does not fix your teeth naturally.  These include patients with every type of cancer.  The dramatic increase of cancer cases in the US in recent times can probably be laid directly on the shoulders of the dentists due to their tireless energies in converting city councils to put fluoride in the water for "the children's teeth."  They are able to do this because of large government grants.  It is irrational to believe just "anything" in the environment causes cancer.  The unique character of fluoride ion in destroying enzymes deserves attention.